There are two main maps in Little Alchemist: Little Town and Little Isles. The original map, Little Town, contains bosses and locations with themes of places you might find in a town, such as a comic book store, pet shop, or graveyard.
The second map, released in mid to late 2014, is Little Isles. Little Isles builds off of the story from Little Town, and includes a more magical island theme, where each island is in it's own right a new world. Little Isles is infinitely more difficult than Little Town and takes a solid deck to totally complete.
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